Maeda H, Ozaki K, Takagi Y, Sawashima K, Narama I
Research Institute of Drug Safety, Setsunan University, Osaka, Japan.
Zentralbl Veterinarmed A. 1994 Apr;41(3):247-50. doi: 10.1111/j.1439-0442.1994.tb00091.x.
Skin lesions were studied in a 3-year-old male Maltese dog with distemper. Hyperkeratosis and parakeratosis with vesicles and pustule formation were the outstanding features of the skin lesions around the eye, nose, and mouth. Multinucleated syncytial giant cells together with nuclear and cytoplasmic inclusion bodies containing viral particles and viral antigen were scattered in the epidermis, and epidermal appendages. These findings suggest a direct viral attack on the skin.
对一只患有犬瘟热的3岁雄性马尔济斯犬的皮肤病变进行了研究。角化过度和不全角化伴水疱和脓疱形成是眼、鼻和口周围皮肤病变的突出特征。多核合胞体巨细胞以及含有病毒颗粒和病毒抗原的核内和胞质内包涵体散在于表皮和表皮附属器中。这些发现提示病毒对皮肤的直接攻击。
