Ojehagen A, Berglund M, Moberg A L
Department of Psychiatry, University of Lund, Sweden.
Alcohol Clin Exp Res. 1994 Jun;18(3):720-5. doi: 10.1111/j.1530-0277.1994.tb00937.x.
The predictors of the long-term outcome in alcoholics (n = 50) who had been treated in a 2-year outpatient treatment program were investigated. Previously, the sample had been followed up personally 2 years after the termination of treatment. This study is a repeated, independent follow-up of the same sample over a 4-year period, 3-6 years after termination of treatment. Outcome could be categorized in 38 subjects. Patients with a favorable outcome during at least 2 years of the 4-year follow-up period (n = 21), who were categorized as a positive outcome group, were compared with the other patients (n = 17). There was no significant correlation between initial patient characteristics and outcome 3-6 years after treatment. Drinking outcome during the 1st half-year of treatment had no correlation to positive drinking outcome in years 3-6, whereas there was a positive correlation for later phases of treatment and outcome reaching a significant level during the 2nd and 4th half-year of treatment. A favorable drinking outcome during years 1-2 after treatment had a positive significant correlation to outcome in years 3-6 after treatment [i.e., 80% of the patients with a favorable outcome during the 1st follow-up period also had a positive outcome during the 2nd follow-up period, and 72% of those who had an unfavorable outcome during the 1st follow-up period had an unfavorable outcome also during the 2nd follow-up period (chi 2 test = 10.4, p < 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
对50名在为期两年的门诊治疗项目中接受治疗的酗酒者的长期预后预测因素进行了调查。此前,该样本在治疗结束后已进行了为期两年的个人随访。本研究是对同一样本在治疗结束后3至6年的4年期间进行的重复、独立随访。38名受试者的预后可进行分类。将在4年随访期内至少2年有良好预后的患者(n = 21)归为阳性预后组,并与其他患者(n = 17)进行比较。治疗后3至6年,初始患者特征与预后之间无显著相关性。治疗前半年的饮酒预后与3至6年的积极饮酒预后无关,而治疗后期与预后呈正相关,在治疗的第2个半年和第4个半年达到显著水平。治疗后1至2年的良好饮酒预后与治疗后3至6年的预后呈显著正相关[即,在第一次随访期有良好预后的患者中,80%在第二次随访期也有良好预后,而在第一次随访期有不良预后的患者中,72%在第二次随访期也有不良预后(卡方检验= 10.4,p < 0.001)。(摘要截选至250字)