Pleiman C M, D'Ambrosio D, Cambier J C
National Jewish Center for Immunology and Respiratory Medicine, Denver, CO 80220.
Immunol Today. 1994 Sep;15(9):393-9. doi: 10.1016/0167-5699(94)90267-4.
The specificity of the immune response is determined by the interaction between the B-cell receptor (BCR) and its cognate structure, antigen. Recent studies have provided considerable insight into the compartmentalization of function within this extremely versatile hetero-oligomeric receptor complex. In this article, Christopher Pleiman, Daniele D'Ambrosio and John Cambier consolidate new findings regarding BCR structure and signal transduction.
