前列腺素F2α（PGF2α）：伤口活力的一个不充分指标？

Prostaglandin F2a (PGF2a): an inadequate marker of the vitality of wounds?

作者信息

Hernández-Cueto C, Vieira D N, Girela E, Marques E, Calvo M D, Villalobos M, Oliveira de Sà F, Villanueva E

机构信息

Department of Legal Medicine and Toxicology, Faculty of Medicine, University of Granada, Spain.

出版信息

Int J Legal Med. 1994;106(6):312-4. doi: 10.1007/BF01224777.

DOI:10.1007/BF01224777

PMID:7947338

Abstract

We have studied the viability of PGF2a as a vitality marker in skin wounds. Incised vital skin wounds and homolateral control pieces of skin were obtained from 20 autopsies performed at the Institute of Legal Medicine of Coimbra University (Portugal). We have also studied 10 fresh skin samples from the Department of Dermatology of the University Hospital (Granada). Our results show that PGF2a is not suitable for the diagnosis of the vitality of wounds because of its irregular behaviour.

摘要

我们研究了前列腺素F2α（PGF2α）作为皮肤伤口活力标志物的可行性。从葡萄牙科英布拉大学法医学研究所进行的20例尸检中获取有活力的皮肤切割伤口及同侧对照皮肤样本。我们还研究了来自格拉纳达大学医院皮肤科的10份新鲜皮肤样本。我们的结果表明，由于PGF2α行为不规律，它不适用于伤口活力的诊断。