Cooper G S, Shlaes D M, Salata R A
Department of Medicine, Case Western Reserve University, Cleveland, Ohio 44106-4984.
Clin Infect Dis. 1994 Jul;19(1):146-8. doi: 10.1093/clinids/19.1.146.
Although the elderly account for a disproportionate number of patients with intraabdominal infections, few studies have compared these patients with younger patients in terms of presentation and outcome. Therefore, we conducted a retrospective cohort study of 131 patients at an urban university hospital that included 88 patients (67%) < or = 65 years of age and 43 (33%) > 65 years of age, all of whom had culture-proven intraabdominal infections. Geriatric patients presented more frequently without the typical symptoms and signs of abdominal pain, nausea and vomiting, diarrhea, and fever and had symptoms for a longer period before presentation. Diagnosis on admission was more often unknown or considered to be of an extraabdominal nature for the elderly patients, and sources of infection were more commonly biliary or pancreatic. Mortality was not significantly different between the groups, but length of stay and duration until normalization of body temperature were longer for the older patients. We concluded that elderly patients with intraabdominal infections frequently present atypically and have a more-protracted course of illness than their younger counterparts.
尽管老年患者在腹腔内感染患者中所占比例过高，但很少有研究在临床表现和治疗结果方面将这些患者与年轻患者进行比较。因此，我们对一家城市大学医院的131例患者进行了一项回顾性队列研究，其中包括88例（67%）年龄≤65岁的患者和43例（33%）年龄>65岁的患者，所有患者均经培养证实患有腹腔内感染。老年患者更常无典型的腹痛、恶心、呕吐、腹泻和发热症状及体征，且在出现症状前持续时间更长。老年患者入院时的诊断往往不明或被认为是腹外性质的，感染源更常见于胆道或胰腺。两组之间的死亡率无显著差异，但老年患者的住院时间和体温恢复正常的持续时间更长。我们得出结论，与年轻患者相比，腹腔内感染的老年患者临床表现往往不典型，病程更长。
