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[肺出血肾炎综合征。一例新病例]

[Goodpasture's syndrome. A new case].

作者信息

Nolen P, Touchard G, d'Eyzac A T, Patte F, Patte D, Morichau-Beauchant G

出版信息

Poumon Coeur. 1976;32(6):325-9.

PMID:794860
Abstract

The authors report a new observation of Goodpasture's syndrome in a 21 years old patient. Diagnosis was made by renal biopsy after discovering, by immunofluorescence techniques, linear deposits of IgG and C3 on the renal basal lamina. Anti-basal lamina antibodies of the plasma were not found. In spite of therapy by steroids, a rapid worsening of renal functions accompanied a nephrotic syndrome. Supplementing hemodialysis helped patients to survive without recurrence of hemoptysis. Heparinotherapy prescribed on the creation of an arteriovenous fistula seemed to have brought a temporary improvement of the renal function.

摘要

作者报告了一名21岁患者患古德帕斯彻综合征的新病例。通过免疫荧光技术在肾基底膜上发现IgG和C3的线性沉积后,经肾活检做出诊断。未发现血浆中的抗基底膜抗体。尽管采用了类固醇治疗,但肾功能迅速恶化并伴有肾病综合征。补充血液透析帮助患者存活且咯血未复发。在建立动静脉瘘时使用肝素治疗似乎使肾功能得到了暂时改善。

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