Garriga G, Stern M J
Department of Molecular and Cell Biology, University of California, Berkeley 94720-3204.
Curr Opin Genet Dev. 1994 Aug;4(4):575-80. doi: 10.1016/0959-437x(94)90075-e.
The analysis of mutations that disrupt egg laying by the Caenorhabditis elegans hermaphrodite has identified genes that are required for the long-range migrations of two cell types, the hermaphrodite-specific neurons and the sex myoblasts. Molecular analysis of some of these genes indicates that transcription factors and signal transduction molecules are necessary for the migrations of these cells.
对秀丽隐杆线虫雌雄同体中破坏产卵的突变进行分析,已鉴定出两种细胞类型(雌雄同体特异性神经元和性成肌细胞)进行长距离迁移所需的基因。对其中一些基因的分子分析表明,转录因子和信号转导分子对于这些细胞的迁移是必需的。