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秀丽隐杆线虫早期胚胎中初始不对称性的建立。

Establishment of initial asymmetry in early Caenorhabditis elegans embryos.

作者信息

Priess J R

机构信息

Department of Basic Science, Fred Hutchinson Cancer Research Center, Seattle, Washington 98104.

出版信息

Curr Opin Genet Dev. 1994 Aug;4(4):563-8. doi: 10.1016/0959-437x(94)90073-c.

DOI:10.1016/0959-437x(94)90073-c
PMID:7950325
Abstract

The Caenorhabditis elegans embryo has anterior/posterior, dorsal/ventral, and left/right axes that correspond to spatially asymmetric patterns of cell differentiation. Recent studies have provided insight into how the different embryonic axes are determined and have shown that the products of the glp-1, skn-1, cap-1, and cap-2 genes appear to be distributed asymmetrically in the early embryo. These gene products should provide important tools for understanding how asymmetries are established initially in nematode embryogenesis.

摘要

秀丽隐杆线虫胚胎具有前/后、背/腹和左/右轴,这些轴与细胞分化的空间不对称模式相对应。最近的研究深入了解了不同胚胎轴是如何确定的,并表明glp-1、skn-1、cap-1和cap-2基因的产物似乎在早期胚胎中不对称分布。这些基因产物应该为理解线虫胚胎发生中不对称性最初是如何建立的提供重要工具。

相似文献

1
Establishment of initial asymmetry in early Caenorhabditis elegans embryos.秀丽隐杆线虫早期胚胎中初始不对称性的建立。
Curr Opin Genet Dev. 1994 Aug;4(4):563-8. doi: 10.1016/0959-437x(94)90073-c.
2
The maternal par genes and the segregation of cell fate specification activities in early Caenorhabditis elegans embryos.秀丽隐杆线虫早期胚胎中的母体par基因与细胞命运决定活性的分离
Development. 1997 Oct;124(19):3815-26. doi: 10.1242/dev.124.19.3815.
3
Genes required for GLP-1 asymmetry in the early Caenorhabditis elegans embryo.秀丽隐杆线虫早期胚胎中GLP-1不对称性所需的基因。
Dev Biol. 1997 Jan 1;181(1):36-46. doi: 10.1006/dbio.1996.8413.
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Signal transduction and cell fate specification during Caenorhabditis elegans vulval development.秀丽隐杆线虫外阴发育过程中的信号转导与细胞命运特化
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The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo.母体基因apx-1和glp-1与秀丽隐杆线虫早期胚胎背腹极性的建立。
Cell. 1994 Apr 8;77(1):95-106. doi: 10.1016/0092-8674(94)90238-0.
6
Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo.母体glp-1 mRNA的翻译控制在秀丽隐杆线虫胚胎中建立了一种不对称性。
Cell. 1994 Apr 22;77(2):183-94. doi: 10.1016/0092-8674(94)90311-5.
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glp-1 and inductions establishing embryonic axes in C. elegans.
Development. 1994 Jul;120(7):2051-64. doi: 10.1242/dev.120.7.2051.
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Combinatorial specification of blastomere identity by glp-1-dependent cellular interactions in the nematode Caenorhabditis elegans.秀丽隐杆线虫中通过glp-1依赖性细胞相互作用对卵裂球身份进行组合式指定。
Development. 1994 Nov;120(11):3325-38. doi: 10.1242/dev.120.11.3325.
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Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm.Wnt信号通路使秀丽隐杆线虫的早期卵裂球极化,从而区分内胚层和中胚层。
Cell. 1997 Aug 22;90(4):695-705. doi: 10.1016/s0092-8674(00)80530-9.
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Reciprocal signaling by Wnt and Notch specifies a muscle precursor in the C. elegans embryo.Wnt和Notch的相互信号传导决定了秀丽隐杆线虫胚胎中的肌肉前体细胞。
Development. 2017 Feb 1;144(3):419-429. doi: 10.1242/dev.145391. Epub 2017 Jan 3.

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Low frequency vibrations disrupt left-right patterning in the Xenopus embryo.低频振动会破坏非洲爪蟾胚胎的左右模式形成。
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Left-right patterning in the C. elegans embryo: Unique mechanisms and common principles.秀丽隐杆线虫胚胎中的左右模式形成:独特机制与共同原理。
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A POP-1 repressor complex restricts inappropriate cell type-specific gene transcription during Caenorhabditis elegans embryogenesis.一种POP-1阻遏物复合物在秀丽隐杆线虫胚胎发生过程中限制不适当的细胞类型特异性基因转录。
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A small conserved domain in the yeast Spa2p is necessary and sufficient for its polarized localization.酵母Spa2p中的一个小保守结构域对其极化定位是必要且充分的。
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Defects in the determination of left-right asymmetry.左右不对称性确定中的缺陷。
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