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内毒素和细胞因子对脂质代谢的影响。

Effects of endotoxin and cytokines on lipid metabolism.

作者信息

Hardardóttir I, Grünfeld C, Feingold K R

机构信息

Department of Medicine, University of California, San Francisco.

出版信息

Curr Opin Lipidol. 1994 Jun;5(3):207-15. doi: 10.1097/00041433-199405030-00008.

DOI:10.1097/00041433-199405030-00008
PMID:7952915
Abstract

Endotoxin, via cytokines, induces marked changes in lipid metabolism: serum VLDL increases, whereas the effect on LDL levels varies among species. The increase in VLDL is caused by stimulation of hepatic VLDL secretion or inhibition of clearance, or both. These alterations can be deleterious or beneficial effects.

摘要

内毒素通过细胞因子诱导脂质代谢发生显著变化

血清极低密度脂蛋白(VLDL)增加,而对低密度脂蛋白(LDL)水平的影响因物种而异。VLDL的增加是由肝脏VLDL分泌的刺激或清除的抑制,或两者共同作用引起的。这些改变可能产生有害或有益的影响。

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