Banerjee A K, Galloway S W, Kingsnorth A N
Department of Surgery, Queen's Medical Centre, Nottingham, UK.
Br J Surg. 1994 Aug;81(8):1096-103. doi: 10.1002/bjs.1800810805.
Various models of experimental acute pancreatitis are described. An ideal model would be reproducible, have a similar natural history to that of the human disease and a similar response to treatment. Furthermore, it should be relatively cheap and simple. Few, if any, of the available experimental models completely satisfy these criteria. The appropriate choice of model is discussed, as are possible future developments in this field.
文中描述了多种实验性急性胰腺炎模型。理想的模型应具有可重复性,其自然病程与人类疾病相似,对治疗的反应也相似。此外,它应该相对便宜且操作简单。现有的实验模型中,几乎没有(如果有的话)能完全满足这些标准。文中讨论了模型的合适选择以及该领域未来可能的发展。