Takahashi S, Ogata Y, Tsuzuki T
Department of Surgery, Keio University, School of Medicine, Tokyo, Japan.
Br J Surg. 1994 Aug;81(8):1190-3. doi: 10.1002/bjs.1800810837.
Between March 1976 and December 1992, 137 (57 per cent) of 239 patients with pancreatic duct cell cancer underwent resection; 79 (58 per cent) of the 137 had combined resection of the pancreas and portal vein. Sixty-three of the 79 patients underwent resection of the portal vein alone; six died (mortality rate 10 per cent). The mortality rate was the same as that in 58 patients with no resection of the portal vein. In the remaining 16 patients adjacent arteries were also resected, with seven deaths. Of patients with resection of the portal vein alone who underwent curative resection, four survived more than 5 years, accounting for nearly half of the nine 5-year survivors. Combined resection of the pancreas and portal vein is associated with both an increased resectability rate and improved long-term survival.
1976年3月至1992年12月期间,239例胰腺导管细胞癌患者中有137例(57%)接受了切除术;137例中有79例(58%)进行了胰腺和门静脉联合切除术。79例患者中有63例仅接受了门静脉切除术;6例死亡(死亡率10%)。该死亡率与58例未切除门静脉的患者相同。其余16例患者还切除了相邻动脉,7例死亡。在仅接受门静脉切除术并进行根治性切除的患者中,4例存活超过5年,占9例5年存活者的近一半。胰腺和门静脉联合切除术既提高了切除率,又改善了长期生存率。