Carty N J, Ravichandran D, Carter C, Mudan S, Royle G T, Taylor I
Breast Unit, Royal South Hants Hospital, Southampton, UK.
Br J Surg. 1994 Sep;81(9):1313-4. doi: 10.1002/bjs.1800810917.
In a minority of patients with a discrete breast lump the initial cytological assessment is either unsatisfactory or at variance with the results of other methods of diagnosis. A randomized comparison of repeat cytology and needle-core biopsy provided clinically useful information in 14 of 31 patients receiving repeat cytology and in 26 of 29 randomized to core biopsy. Nineteen patients had carcinoma: ten who received repeat cytology, which indicated malignancy in only three (diagnostic of malignancy in one, suspicious in two), while all nine patients who underwent core biopsy had a correct diagnosis (only suspicious of malignancy in one). The sensitivity for the definitive diagnosis of carcinoma on repeat cytology and core biopsy was 10 and 89 per cent respectively. Patients with a discrete breast lump and unclear cytology results require needle-core biopsy. This has more diagnostic value than repeat cytology.
在少数有孤立性乳腺肿块的患者中，最初的细胞学评估要么不令人满意，要么与其他诊断方法的结果不一致。对重复细胞学检查和针芯活检进行的随机比较显示，在接受重复细胞学检查的31例患者中有14例、在随机接受针芯活检的29例患者中有26例获得了临床有用信息。19例患者患有癌症：10例接受了重复细胞学检查，其中仅3例提示恶性（1例诊断为恶性，2例可疑），而接受针芯活检的9例患者均得到了正确诊断（仅1例可疑恶性）。重复细胞学检查和针芯活检对癌症确诊的敏感性分别为10%和89%。有孤立性乳腺肿块且细胞学结果不明确的患者需要进行针芯活检。这比重复细胞学检查具有更大的诊断价值。
