Shoji N, Umeyama A, Yoshikawa K, Arihara S
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan.
Chem Pharm Bull (Tokyo). 1994 Sep;42(9):1750-5. doi: 10.1248/cpb.42.1750.
From the herb of Anagallis arvensis L., we have isolated five novel oleanane glycosides, anagallosaponins I-V and the artifact, methyl anagallosaponin I, besides anagallosides A, B, C, and desglucoanagallosides A and B. The structures of isolates were identified by the use of 2D-NMR techniques (1H-1H correlation spectroscopy (COSY), 1H-detected heteronuclear multiple quantum coherence (HMQC), heteronuclear multiple quantum coherence (HMBC), rotating frame Overhauser enhancement spectroscopy (ROESY), total correlation spectroscopy (TOCSY). The structures of anagallosaponins I and II were characterized as anagallogenin A. 3-O-(beta-D-glucopyranosyl (1-->4)-[beta-D-xylopyranosyl (1-->2)-] beta-D-glucopyranosyl (1-->4)- [beta-D-glucopyranosyl (1-->2)]-alpha-L-arabinopyranoside) and anagallogein A 22-acetate 3-O-(beta-D-xylopyranosyl (1-->2)-O-beta-D- glucopyranosyl (1-->4)-[beta-D-glucopyranosyl (1-->2)]-alpha-L-arabinopyranoside), respectively. The structures of anagallosaponins III, IV and V were characterized as priverogenin B 22-acetate 3-O-beta-D-xylopyranosyl (1-->2)-beta-D-glucopyranosyl (1-->4)-alpha-L-arabinopyranoside, 3-O-(beta-D-xylopyranosyl (1-->2)-beta-D-glucopyranosyl (1-->4)-[beta-D-glucopyranosyl (1-->2)]-alpha-L-arabinopyranoside), 3-O-(beta-D-glucopyranosyl (1-->4)-[beta-D-xylopyranosyl (1-->2)]-beta-D-glucopyranosyl (1-->4)-alpha-L-arabinopyranoside), respectively. Methyl anagallosaponin I, the methylacetal of anagallosaponin I might be derived from anagallosaponin I during the isolation procedure.
从草本植物小ag草（Anagallis arvensis L.）中，我们除了分离出小ag苷A、B、C以及去葡萄糖小ag苷A和B之外，还分离出了5种新型齐墩果烷糖苷，即小ag皂苷I - V以及人工产物甲基小ag皂苷I。通过使用二维核磁共振技术（1H-1H相关光谱法（COSY）、1H检测的异核多量子相干（HMQC）、异核多量子相干（HMBC）、旋转框架奥弗豪泽增强光谱法（ROESY）、全相关光谱法（TOCSY））确定了分离物的结构。小ag皂苷I和II的结构被表征为小ag配基A. 3 - O -（β - D - 吡喃葡萄糖基（1→4） - [β - D - 吡喃木糖基（1→2） - ]β - D - 吡喃葡萄糖基（1→4） - [β - D - 吡喃葡萄糖基（1→2）] - α - L - 阿拉伯吡喃糖苷）和小ag配基A 22 - 乙酸酯3 - O -（β - D - 吡喃木糖基（1→2） - O - β - D - 吡喃葡萄糖基（1→4） - [β - D - 吡喃葡萄糖基（1→2）] - α - L - 阿拉伯吡喃糖苷），分别。小ag皂苷III、IV和V的结构被表征为原卫矛醇配基B 22 - 乙酸酯3 - O - β - D - 吡喃木糖基（1→2） - β - D - 吡喃葡萄糖基（1→4） - α - L - 阿拉伯吡喃糖苷、3 - O -（β - D - 吡喃木糖基（1→2） - β - D - 吡喃葡萄糖基（1→4） - [β - D - 吡喃葡萄糖基（1→2）] - α - L - 阿拉伯吡喃糖苷）、3 - O -（β - D - 吡喃葡萄糖基（1→4） - [β - D - 吡喃木糖基（1→2）] - β - D - 吡喃葡萄糖基（1→4） - α - L - 阿拉伯吡喃糖苷），分别。甲基小ag皂苷I，即小ag皂苷I的甲基缩醛，可能是在分离过程中由小ag皂苷I衍生而来。
