匙羹藤中的齐墩果烷皂苷。

Oleanane saponins from Gymnema sylvestre.

作者信息

Ye W C, Zhang Q W, Liu X, Che C T, Zhao S X

机构信息

Department of Chemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.

出版信息

Phytochemistry. 2000 Apr;53(8):893-9. doi: 10.1016/s0031-9422(99)00483-5.

DOI:10.1016/s0031-9422(99)00483-5

PMID:10820799

Abstract

Six oleanane-type saponins, along with two known triterpene saponins, were isolated from the leaves of Gymnema sylvestre. The structures of the oleanane triterpene glycosides were characterized as longispinogenin 3-O-beta-D-glucuronopyranoside, 21 beta-benzoylsitakisogenin 3-O-beta-D-glucuronopyranoside, 3-O-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranosyl oleanolic acid 28-O-beta-D-glucopyranosyl ester, oleanolic acid 3-O-beta-D-xylopyranosyl(1-->6)-beta-D-glucopyranosyl(1-->6)-beta-D- glucopyranoside, 3-O-beta-D-xylopyranosyl(1-->6)-beta-D-glucopyranosyl (1-->6)-beta-D-glucopyranosyl oleanolic acid 28-O-beta-D-glucopyranosyl ester and 3-O-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranosyl oleanolic acid 28-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranosyl ester on the basis of hydrolysis and spectral evidence, including 1D- and 2D-NMR (TOCSY, ROESY, HMQC and HMBC) and FABMS analyses.

摘要

从匙羹藤叶中分离出六种齐墩果烷型皂苷以及两种已知的三萜皂苷。基于水解和光谱证据，包括一维和二维核磁共振（TOCSY、ROESY、HMQC和HMBC）以及快原子轰击质谱（FABMS）分析，将齐墩果烷三萜糖苷的结构鉴定为长刺皂苷元3 - O - β - D - 葡糖醛酸吡喃糖苷、21β - 苯甲酰基丝石竹皂苷元3 - O - β - D - 葡糖醛酸吡喃糖苷、3 - O - β - D - 吡喃葡糖基(1→6)-β - D - 吡喃葡糖基齐墩果酸28 - O - β - D - 吡喃葡糖基酯、齐墩果酸3 - O - β - D - 吡喃木糖基(1→6)-β - D - 吡喃葡糖基(1→6)-β - D - 吡喃葡糖苷、3 - O - β - D - 吡喃木糖基(1→6)-β - D - 吡喃葡糖基(1→6)-β - D - 吡喃葡糖基齐墩果酸28 - O - β - D - 吡喃葡糖基酯以及3 - O - β - D - 吡喃葡糖基(1→6)-β - D - 吡喃葡糖基齐墩果酸28 - β - D - 吡喃葡糖基(1→6)-β - D - 吡喃葡糖基酯。