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涎腺腺样囊性癌的免疫电子显微镜及免疫组织化学研究

[Immunoelectron microscopic and immunohistochemical study of adenoid cystic carcinoma of the salivary gland].

作者信息

Wang J, Wu Q G, Sun K H

机构信息

School of Stomatology, Beijing Medical University.

出版信息

Zhonghua Bing Li Xue Za Zhi. 1994;23(3):173-5.

PMID:7954959
Abstract

Four adenoid cystic carcinomas of salivary gland were studied by immunohistochemistry and immunoelectron microscopy with anti-actin, myosin, S-100 protein and GFAP antibodies. The results showed that neoplastic myoepithelial cells in these tumors gave positive reactions for actin, myosin and S-100 protein antibodies and negative reactions for GFAP antibody. The neoplastic myoepithelial cells lined the cyst-like spaces and surrounded the periphery of the epithelial nests. Neoplastic ductal epithelial cells were negative for the above mentioned antibodies. The differentiation tendencies and immunofeatures of neoplastic myoepithelial cells were discussed.

摘要

采用抗肌动蛋白、肌球蛋白、S - 100蛋白和胶质纤维酸性蛋白(GFAP)抗体,通过免疫组织化学和免疫电子显微镜技术对4例涎腺腺样囊性癌进行了研究。结果显示,这些肿瘤中的肿瘤性肌上皮细胞对肌动蛋白、肌球蛋白和S - 100蛋白抗体呈阳性反应,而对GFAP抗体呈阴性反应。肿瘤性肌上皮细胞排列在囊样间隙内,并围绕上皮巢的周边。肿瘤性导管上皮细胞对上述抗体呈阴性反应。对肿瘤性肌上皮细胞的分化趋势和免疫特征进行了讨论。

相似文献

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[Immunoelectron microscopic and immunohistochemical study of adenoid cystic carcinoma of the salivary gland].涎腺腺样囊性癌的免疫电子显微镜及免疫组织化学研究
Zhonghua Bing Li Xue Za Zhi. 1994;23(3):173-5.
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The role of Schwann cell differentiation in perineural invasion of adenoid cystic and mucoepidermoid carcinoma of the salivary glands.施万细胞分化在涎腺腺样囊性癌和黏液表皮样癌神经周浸润中的作用
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Virchows Arch. 2002 May;440(5):536-42. doi: 10.1007/s00428-001-0585-6. Epub 2002 Feb 9.
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Polymorphous low-grade adenocarcinoma of minor salivary gland. A comparative histologic and immunohistochemical study.小唾液腺多形性低度恶性腺癌。一项组织学与免疫组化对比研究。
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[Myoepithelial differentiation markers in salivary gland neoplasia].[唾液腺肿瘤中的肌上皮分化标志物]
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Expression of S-100 protein and glial fibrillary acidic protein in cultured submandibular gland epithelial cells and salivary gland tissues. Histogenetic implication for salivary gland tumors.培养的下颌下腺上皮细胞和唾液腺组织中S-100蛋白和胶质纤维酸性蛋白的表达。对唾液腺肿瘤的组织发生学意义。
Am J Pathol. 1996 May;148(5):1709-16.
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Myoepithelial tumors of salivary glands: a clinicopathologic, immunohistochemical, ultrastructural, and flow-cytometric study.唾液腺肌上皮肿瘤:一项临床病理、免疫组织化学、超微结构及流式细胞术研究
Semin Diagn Pathol. 1996 May;13(2):138-47.
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[Study of electron microscopy histochemistry and immunohistochemistry of extracellular matrix in adenoid cystic carcinoma].腺样囊性癌细胞外基质的电镜组织化学与免疫组织化学研究
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A hybrid carcinoma: adenoid cystic carcinoma and salivary duct carcinoma of the salivary gland. An immunohistochemical study.一种混合性癌:涎腺腺样囊性癌和涎腺导管癌。一项免疫组织化学研究。
Virchows Arch. 1997 Jun;430(6):495-500. doi: 10.1007/s004280050060.

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