Wang J, Wu Q G, Sun K H
School of Stomatology, Beijing Medical University.
Zhonghua Bing Li Xue Za Zhi. 1994;23(3):173-5.
Four adenoid cystic carcinomas of salivary gland were studied by immunohistochemistry and immunoelectron microscopy with anti-actin, myosin, S-100 protein and GFAP antibodies. The results showed that neoplastic myoepithelial cells in these tumors gave positive reactions for actin, myosin and S-100 protein antibodies and negative reactions for GFAP antibody. The neoplastic myoepithelial cells lined the cyst-like spaces and surrounded the periphery of the epithelial nests. Neoplastic ductal epithelial cells were negative for the above mentioned antibodies. The differentiation tendencies and immunofeatures of neoplastic myoepithelial cells were discussed.
采用抗肌动蛋白、肌球蛋白、S - 100蛋白和胶质纤维酸性蛋白(GFAP)抗体,通过免疫组织化学和免疫电子显微镜技术对4例涎腺腺样囊性癌进行了研究。结果显示,这些肿瘤中的肿瘤性肌上皮细胞对肌动蛋白、肌球蛋白和S - 100蛋白抗体呈阳性反应,而对GFAP抗体呈阴性反应。肿瘤性肌上皮细胞排列在囊样间隙内,并围绕上皮巢的周边。肿瘤性导管上皮细胞对上述抗体呈阴性反应。对肿瘤性肌上皮细胞的分化趋势和免疫特征进行了讨论。