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胺碘酮诱发的血管炎及胺碘酮皮肤副作用综述。

Amiodarone-induced vasculitis and a review of the cutaneous side-effects of amiodarone.

作者信息

Dootson G, Byatt C

机构信息

Department of Dermatology, Queen Elizabeth Hospital, King's Lynn, Norfolk, UK.

出版信息

Clin Exp Dermatol. 1994 Sep;19(5):422-4. doi: 10.1111/j.1365-2230.1994.tb02701.x.

Abstract

Amiodarone is a valuable agent, used in the management of intractable cardiac arrhythmias. Its widespread use persists despite a list of well recognized side-effects. Skin reactions are common, usually presenting as photosensitivity or less frequently as a blue/grey pigmentation on light-exposed sites. Leucocytoclastic vasculitis following treatment with amiodarone has been reported rarely. We describe a further case and briefly review the unwanted cutaneous manifestations of amiodarone therapy.

摘要

胺碘酮是一种有价值的药物,用于治疗顽固性心律失常。尽管有一系列公认的副作用,但它仍被广泛使用。皮肤反应很常见,通常表现为光敏性,较少见的是在暴露部位出现蓝/灰色色素沉着。胺碘酮治疗后发生白细胞破碎性血管炎的报道很少。我们描述了另一例病例,并简要回顾了胺碘酮治疗的不良皮肤表现。

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