Taaffe D R, Lewis B, Marcus R
Musculoskeletal Research Laboratory, Veterans Affairs Medical Center, Palo Alto, CA 943904.
Clin Physiol. 1994 Jul;14(4):393-404. doi: 10.1111/j.1475-097x.1994.tb00398.x.
The purpose of this study was to quantify the effect that hand preference has on upper limb bone mineral and soft tissue composition in healthy young and elderly women. Bone mineral content (BMC) in grams, bone mineral density (BMD) in g cm-2, fat-free soft tissue (FFST) in grams, fat tissue (g), and percent fat were determined by dual-energy X-ray absorptiometry (DXA) for dominant and non-dominant upper limbs as well as total body fat (%) in 25 young (26.6 +/- 4.3 years, mean +/- SD) and 35 elderly women (68.4 +/- 2.9 years). For both groups, the dominant upper limb had a greater BMC (P < 0.001), BMD (young, P < 0.001; elderly, P < 0.05), and FFST mass (P < 0.001), and a lower percent fat (young, P < 0.01; elderly, P < 0.05) than the non-dominant limb; however, there was no difference between limbs for total fat mass. BMC, BMD, and FFST in the dominant limb of young women were 7.1%, 1.8%, and 5.1% greater than the non-dominant limb, while for older women the differences were 5.3%, 1.0%, and 4.2%. Relative fat of the dominant limb was 3.0% and 1.3% less than the non-dominant limb for young and older women, respectively. Age did not affect the percent bone mineral or soft tissue difference. A higher bone mineral and FFST mass in the dominant limb is expected due to the greater activity demands placed upon these tissues. However, a larger bone and FFST mass increases the total mass of the dominant limb, resulting in a dilution of the fat tissue mass and hence a reduced fat percent for the limb. This study indicates that hand preference affects the tissue composition of the upper limb in both young and elderly women, resulting in an increased bone mineral and FFST mass with no change in absolute fat mass. Hand preference should be taken into account when upper limb bone mineral and/or soft tissue composition is assessed.
本研究的目的是量化惯用手对健康年轻和老年女性上肢骨矿物质及软组织成分的影响。通过双能X线吸收法（DXA）测定了25名年轻女性（26.6±4.3岁，均值±标准差）和35名老年女性（68.4±2.9岁）优势上肢和非优势上肢的骨矿物质含量（BMC，单位为克）、骨矿物质密度（BMD，单位为g/cm²）、无脂肪软组织（FFST，单位为克）、脂肪组织（单位为克）以及脂肪百分比，同时还测定了全身脂肪百分比（%）。对于两组人群，优势上肢的BMC（P<0.001）、BMD（年轻组，P<0.001；老年组，P<0.05）和FFST质量（P<0.001）均高于非优势上肢，且脂肪百分比更低（年轻组，P<0.01；老年组，P<0.05）；然而，两上肢的总脂肪质量无差异。年轻女性优势上肢的BMC、BMD和FFST分别比非优势上肢高7.1%、1.8%和5.1%，而老年女性的差异分别为5.3%、1.0%和4.2%。年轻和老年女性优势上肢的相对脂肪分别比非优势上肢少3.0%和1.3%。年龄不影响骨矿物质或软组织差异的百分比。由于优势上肢的这些组织有更高的活动需求，预计其骨矿物质和FFST质量会更高。然而，更大的骨骼和FFST质量会增加优势上肢的总质量，导致脂肪组织质量稀释，从而使该上肢的脂肪百分比降低。本研究表明，惯用手会影响年轻和老年女性上肢的组织成分，导致骨矿物质和FFST质量增加，而绝对脂肪质量无变化。在评估上肢骨矿物质和/或软组织成分时应考虑惯用手因素。
