Li H G, Ma Z T, He Q
Department of Orthopedic Surgery, First Hospital of Beijing Medical University.
Zhonghua Zhong Liu Za Zhi. 1994 May;16(3):199-202.
Twelve patients with advanced osteosarcoma were treated with fast neutron at the Neutron Therapy Facility, the Hight-Energy Physics Institute, Chinese Academy of Science. Of the 12 patients, 5 were operated after radiotherapy. Three of them received fast neutron alone, and the other 2 with added 60Co. The doses ranged from 660 NcGy to 2 168 NcGy. Pain was relieved and the tumor size decreased in all the treated patients. Only one case was found histologically free of viable tumor cells. Skin reaction was serious and the knee joint function was impaired in all patients.
12例晚期骨肉瘤患者在中国科学院高能物理研究所中子治疗装置接受快中子治疗。12例患者中，5例在放疗后接受了手术。其中3例仅接受快中子治疗，另外2例加用了60钴。剂量范围为660纳库仑每克至2168纳库仑每克。所有接受治疗的患者疼痛均得到缓解，肿瘤大小减小。仅1例经组织学检查未发现存活肿瘤细胞。所有患者皮肤反应严重，膝关节功能均受损。
