Li H G, Ma Z T, He Q
Department of Orthopedic Surgery, First Hospital of Beijing Medical University.
Zhonghua Zhong Liu Za Zhi. 1994 May;16(3):199-202.
Twelve patients with advanced osteosarcoma were treated with fast neutron at the Neutron Therapy Facility, the Hight-Energy Physics Institute, Chinese Academy of Science. Of the 12 patients, 5 were operated after radiotherapy. Three of them received fast neutron alone, and the other 2 with added 60Co. The doses ranged from 660 NcGy to 2 168 NcGy. Pain was relieved and the tumor size decreased in all the treated patients. Only one case was found histologically free of viable tumor cells. Skin reaction was serious and the knee joint function was impaired in all patients.