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扎伊尔北部地区HIV感染的流行病学及临床表现

Epidemiology and clinical manifestation of HIV infection in northern Zaire.

作者信息

Strecker W, Gürtler L, Schilling M, Binibangili M, Strecker K

机构信息

Department of Traumatology, University of Ulm, Germany.

出版信息

Eur J Epidemiol. 1994 Feb;10(1):95-8. doi: 10.1007/BF01717460.

DOI:10.1007/BF01717460
PMID:7957799
Abstract

1275 patients were evaluated for HIV-1 + 2 seroprevalence and its association with clinical symptoms of HIV infection. Of 667 apparently healthy subjects, 8.2% had anti-HIV-1 antibodies. In 465 patients with clinical signs of AIDS, 39.4% were seropositive. 143 patients with miscellaneous symptoms had positive predictive values for HIV infection between 67% (vaginal ulcerations) and 20% (profound pyogenic abscesses). The WHO definition for AIDS had a specificity of 78.3%, a sensitivity of 72.2% and a predictive value of 61.6%.

摘要

对1275名患者进行了HIV-1和HIV-2血清阳性率及其与HIV感染临床症状关联的评估。在667名看似健康的受试者中,8.2%的人有抗HIV-1抗体。在465名有艾滋病临床体征的患者中,39.4%为血清阳性。143名有各种症状的患者中,HIV感染的阳性预测值在67%(阴道溃疡)至20%(严重化脓性脓肿)之间。世界卫生组织对艾滋病的定义特异性为78.3%,敏感性为72.2%,预测值为61.6%。

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