非洲获得性免疫缺陷综合征临床病例定义的评估。
Evaluation of a clinical case-definition of acquired immunodeficiency syndrome in Africa.
作者信息
Colebunders R, Mann J M, Francis H, Bila K, Izaley L, Kakonde N, Kabasele K, Ifoto L, Nzilambi N, Quinn T C
出版信息
Lancet. 1987 Feb 28;1(8531):492-4. doi: 10.1016/s0140-6736(87)92099-x.
A provisional clinical case-definition for acquired immunodeficiency syndrome (AIDS) developed by the World Health Organisation (WHO) for use in Africa was tested on 174 inpatients at Mama Yemo Hospital, Kinshasa, Zaire. In this hospital population with a 34% infection rate of human immunodeficiency virus (HIV), the clinical case-definition had a specificity of 90%, a sensitivity of 59%, and a predictive value of 74% for HIV seropositivity. These results support the use of the WHO clinical definition for AIDS in Africa. However, since HIV prevalence and disease expression vary, similar evaluations should be carried out in different regions.
世界卫生组织（WHO）制定的用于非洲的获得性免疫缺陷综合征（AIDS）临时临床病例定义，在扎伊尔金沙萨耶莫妈妈医院的174名住院患者身上进行了测试。在这个人类免疫缺陷病毒（HIV）感染率为34%的医院人群中，该临床病例定义对HIV血清阳性的特异性为90%，敏感性为59%，预测值为74%。这些结果支持在非洲使用WHO的AIDS临床定义。然而，由于HIV流行率和疾病表现存在差异，应在不同地区进行类似评估。
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