Prokhorova A V, Voloshina M A, Shostak N G, Barskiĭ V E, Golubovskiĭ M D
Genetika. 1994 Jul;30(7):874-8.
Transformation of Drosophila melanogaster using P-element-based vectors yielded 129 sublines, which carried mini-white gene copies in the different genome regions. Dependence of mini-white gene expression on the location, gene dosage, and sex of the transformed individuals was analyzed. The mutation lzb was shown to suppress mini-white gene expression, the degree of suppression depending on the location and dosage of the mini-white gene.
使用基于P因子的载体对黑腹果蝇进行转化产生了129个亚系,这些亚系在不同的基因组区域携带了小白色基因拷贝。分析了小白色基因表达对转化个体的位置、基因剂量和性别的依赖性。结果表明,突变lzb可抑制小白色基因的表达,抑制程度取决于小白色基因的位置和剂量。