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[果蝇黑腹转化体品系w'lz(b)/XXywf的制备及初步遗传分析，该品系在依赖P因子的转化过程中，基因组中整合了微型白色基因]

[Preparation and primary genetic analysis of Drosophila melanogaster transformants line w'lz(b)/XXywf, containing mini-white genes, integrated in the genome during P-element-dependent transformation].

作者信息

Prokhorova A V, Voloshina M A, Shostak N G, Barskiĭ V E, Golubovskiĭ M D

出版信息

Genetika. 1994 Jul;30(7):874-8.

PMID:7958802
Abstract

Transformation of Drosophila melanogaster using P-element-based vectors yielded 129 sublines, which carried mini-white gene copies in the different genome regions. Dependence of mini-white gene expression on the location, gene dosage, and sex of the transformed individuals was analyzed. The mutation lzb was shown to suppress mini-white gene expression, the degree of suppression depending on the location and dosage of the mini-white gene.

摘要

使用基于P因子的载体对黑腹果蝇进行转化产生了129个亚系，这些亚系在不同的基因组区域携带了小白色基因拷贝。分析了小白色基因表达对转化个体的位置、基因剂量和性别的依赖性。结果表明，突变lzb可抑制小白色基因的表达，抑制程度取决于小白色基因的位置和剂量。

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