Grandas F, Esteban A
Servicio de Neurología, Hospital General Gregorio Marañón, Madrid, Spain.
J Neural Transm Suppl. 1994;42:33-41. doi: 10.1007/978-3-7091-6641-3_3.
Eyelid motor abnormalities found in progressive supranuclear palsy are reviewed. Electrophysiological correlates of blepharospasm, levator inhibition (blepharokolysis) and supranuclear paralysis of lid closure are presented. Disorders of eyelid motility are not uncommon in progressive supranuclear palsy (PSP). They may be found in about one third of patients with this syndrome (Jackson et al., 1983; Golbe et al., 1989). This is not surprising since ocular and eyelid movements are highly coordinated, mainly in the vertical plane (Gordon, 1951; Kennard and Smith, 1963; Kennard and Glaser, 1964), and a supranuclear ophthalmoplegia with down gaze impairment is a cardinal feature of PSP (Steele et al., 1964). The spectrum of eyelid motor disorders described in PSP includes blinking abnormalities, lid retraction, blepharospasm, levator inhibition and supranuclear palsy of eye closure.
本文综述了进行性核上性麻痹中发现的眼睑运动异常。文中介绍了眼睑痉挛、提上睑肌抑制（眼睑松解）和核上性眼睑闭合麻痹的电生理相关性。眼睑运动障碍在进行性核上性麻痹（PSP）中并不少见。约三分之一的该综合征患者可能出现此类症状（Jackson等人，1983年；Golbe等人，1989年）。这并不奇怪，因为眼球和眼睑运动高度协调，主要在垂直平面上（Gordon，1951年；Kennard和Smith，1963年；Kennard和Glaser，1964年），而下视障碍的核上性眼肌麻痹是PSP的主要特征（Steele等人，1964年）。PSP中描述的眼睑运动障碍谱包括眨眼异常、眼睑退缩、眼睑痉挛、提上睑肌抑制和核上性眼睑闭合麻痹。
