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腭上皮内神经末梢及其对蛙腭上皮纤毛活动的调节

Intra-epithelial palatine nerve endings and their regulation of ciliary activity of frog palate epithelium.

作者信息

Chu S, Kennedy J R

机构信息

Department of Zoology, University of Tennessee, Knoxville 37996.

出版信息

J Comp Physiol A. 1994 Oct;175(4):505-18. doi: 10.1007/BF00199257.

DOI:10.1007/BF00199257
PMID:7965919
Abstract
  1. Direct contact between intra-epithelial nerve endings and ciliated cells was observed in frog (Rana pipiens) palate epithelium. 2. Electrical stimulation of the palatine nerve to the explant or the explant culture induced an increase in ciliary beat frequency in explant and outgrowth cells. 3. Atropine inhibited electrically stimulated ciliary beat frequency increase in the explant and outgrowth cells. 4. Gap junctional intercellular communication appears to be involved in the propagation of stimulated ciliary beat frequency increase from innervated to non-innervated ciliated cells.
摘要
  1. 在青蛙(豹蛙)腭上皮中观察到上皮内神经末梢与纤毛细胞之间的直接接触。2. 对植块或植块培养物的腭神经进行电刺激,可诱导植块和生长细胞中的纤毛摆动频率增加。3. 阿托品抑制了植块和生长细胞中电刺激引起的纤毛摆动频率增加。4. 间隙连接细胞间通讯似乎参与了刺激引起的纤毛摆动频率增加从受神经支配的纤毛细胞向未受神经支配的纤毛细胞的传播。

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引用本文的文献

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Substance P and acetylcholine are co-localized in the pathway mediating mucociliary activity in Rana pipiens.P物质和乙酰胆碱共定位于介导豹蛙黏液纤毛活动的通路中。
Comp Biochem Physiol B Biochem Mol Biol. 2007 Apr;146(4):477-81. doi: 10.1016/j.cbpb.2006.11.012. Epub 2006 Nov 25.
2
The mechanism of ciliary stimulation by acetylcholine: roles of calcium, PKA, and PKG.乙酰胆碱刺激纤毛的机制:钙、蛋白激酶A和蛋白激酶G的作用。
J Gen Physiol. 2002 Apr;119(4):329-39. doi: 10.1085/jgp.20028519.
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本文引用的文献

1
Some features of the submicroscopic morphology of synapses in frog and earthworm.青蛙和蚯蚓突触的亚显微形态学的一些特征。
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Synapses in the central nervous system.中枢神经系统中的突触。
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3
Structure of rapidly frozen gap junctions.快速冷冻间隙连接的结构。
有机磷杀虫剂毒死蜱和氯蜱硫磷对离体青蛙腭部纤毛上皮的影响。
Arch Environ Contam Toxicol. 1996 Feb;30(2):188-94. doi: 10.1007/BF00215797.
J Cell Biol. 1980 Oct;87(1):273-9. doi: 10.1083/jcb.87.1.273.
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Innervation of the mucosa of rabbit maxillary sinus. I. Electron microscopic findings.兔上颌窦黏膜的神经支配。I. 电子显微镜观察结果
Acta Otolaryngol. 1982 Sep-Oct;94(3-4):345-50. doi: 10.3109/00016488209128922.
6
Cholinergic nerves stimulate mucociliary transport, ciliary activity, and mucus secretion in the frog palate.
Cell Tissue Res. 1982;227(2):413-21. doi: 10.1007/BF00210895.
7
Suppression of mucus secretion in the ciliated epithelium of frog palatine mucosa by perfusion with electrolyte solution.
Jpn J Pharmacol. 1982 Apr;32(2):237-45. doi: 10.1254/jjp.32.237.
8
Dopaminergic innervation and inhibition of ciliary movement in the ciliated epithelium of frog palatine mucosa.蛙腭黏膜纤毛上皮中的多巴胺能神经支配与纤毛运动抑制
Eur J Pharmacol. 1983 Jun 17;90(4):325-31. doi: 10.1016/0014-2999(83)90553-8.
9
Stimulation of mucus secretion, ciliary activity, and transport in frog palate epithelium.刺激青蛙腭上皮中的黏液分泌、纤毛活动和转运。
Am J Physiol. 1984 Nov;247(5 Pt 1):C299-308. doi: 10.1152/ajpcell.1984.247.5.C299.
10
Conflicting effects of noradrenaline on ciliary movement of frog palatine mucosa.去甲肾上腺素对青蛙腭黏膜纤毛运动的矛盾作用。
Eur J Pharmacol. 1984 Jan 27;97(3-4):239-45. doi: 10.1016/0014-2999(84)90455-2.