镇静剂及其溶剂对中性粒细胞功能的影响。
Effects of sedatives and their solvents on the neutrophil granulocyte function.
作者信息
Tian Y K, Weiss M, Schneider M
机构信息
Department of Anesthesiology, Tongji Hospital, Tongji Medical University, Wuhan.
出版信息
J Tongji Med Univ. 1994;14(2):85-8.
PMID:7966520
Abstract
We have examined the effects of commercially available preparations and drug-free solvents of Midazolam (Dormicum) and Propofol (Disoprivan) by N-formyl-methionyl-leucyl-phenylalanine (FMLP) -induced polymorphonuclear cell (PMN) chemiluminescence system. In the case of propofol and drug-free solvent, PMN chemiluminescence was suppressed. With Midazolam, only the active drug depressed PMN chemiluminescence.
摘要
我们通过N-甲酰甲硫氨酰-亮氨酰-苯丙氨酸（FMLP）诱导的多形核白细胞（PMN）化学发光系统，研究了咪达唑仑（多美康）和丙泊酚（得普利麻）的市售制剂及无药溶剂的作用。对于丙泊酚及其无药溶剂，PMN化学发光受到抑制。对于咪达唑仑，只有活性药物能抑制PMN化学发光。
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