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Anomalies in the selection of mutants of Schizosaccharomyces pombe resistant to 8-azaguanine.

作者信息

McAthey P

出版信息

Mol Gen Genet. 1976 Dec 8;149(2):239-41. doi: 10.1007/BF00332895.

DOI:10.1007/BF00332895
PMID:796682
Abstract

Anomalies in selection render 8-azaguanine unsuitable as a selective agent for screening forward mutations in continuour cultures of Sch. pombe. This system may, however, provide tha basis for an enrichment method for the simultaneous isolation of mutants at two loci.

摘要

相似文献

1
Anomalies in the selection of mutants of Schizosaccharomyces pombe resistant to 8-azaguanine.
Mol Gen Genet. 1976 Dec 8;149(2):239-41. doi: 10.1007/BF00332895.
2
Mutants of Eremothecium ashbyii resistant to 8-azaguanine. Communication I. Isolation of mutants and study of the level of riboflavin biosynthesis.
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3
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4
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Genetika. 1975;11(6):95-104.
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Extrachromosomal inheritance in Schizosaccharomyces pombe. IV. Isolation and genetic characterization of mutants resistant to chloramphenicol and erythromycin using the mutator properties of mutant anar-8.粟酒裂殖酵母中的染色体外遗传。IV. 利用突变体anar-8的诱变特性分离对氯霉素和红霉素耐药的突变体并进行遗传特征分析。
Mol Gen Genet. 1977 Oct 24;155(3):339-46. doi: 10.1007/BF00272814.
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[Eremothecium ashbyii mutants resistant to 8-azaguanine. III. Nucleotide pyrophosphorylase activity of mutants with a varying degree of 8-azaguanine resistance].[阿舒假囊酵母8-氮杂鸟嘌呤抗性突变体。III. 不同程度8-氮杂鸟嘌呤抗性突变体的核苷酸焦磷酸化酶活性]
Genetika. 1982 May;18(5):732-5.

本文引用的文献

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Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro.哺乳动物细胞遗传学。II. 体外化学诱导中国仓鼠细胞特定基因座突变
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The role of 8-azaguanine in the selection from human diploid cells of mutants deficient in hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT).8-氮杂鸟嘌呤在从人二倍体细胞中筛选次黄嘌呤-鸟嘌呤磷酸核糖转移酶（HGPRT）缺陷型突变体中的作用。
Mutat Res. 1974 Jul;24(1):55-68. doi: 10.1016/0027-5107(74)90047-5.
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The spontaneous azaguanine-resistant mutants of diploid human fibroblasts.二倍体人成纤维细胞的自发氮鸟嘌呤抗性突变体。
Humangenetik. 1972;16(1):87-110. doi: 10.1007/BF00393992.
8
Altered enzymes in drug-resistant variants of mammalian tissue culture cells.哺乳动物组织培养细胞耐药变体中的酶改变
Proc Natl Acad Sci U S A. 1973 Nov;70(11):3145-9. doi: 10.1073/pnas.70.11.3145.
9
Regulation of the biosynthesis of purine nucleotides in Schizosaccharomyces pombe. I. Properties of the phosphoribosylpyrophosphate: glutamine amidotransferase of the wild strain and of a mutant desensitized towards feedback modifiers.
Biochim Biophys Acta. 1970 Mar 18;198(3):471-81. doi: 10.1016/0005-2744(70)90125-7.
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Mutants of Neurospora crassa resistant to 8-azaguanine.对8-氮杂鸟嘌呤具有抗性的粗糙脉孢菌突变体。
J Gen Microbiol. 1974 Aug;83(2):319-26. doi: 10.1099/00221287-83-2-319.