Burczak K, Rosiak J
Miedzyresortowy Instytut Techniki Radiacyjnej Politechniki Lódzkiej w Lodzi.
Polim Med. 1994;24(1-2):45-55.
The authors present a review of works done on the elaboration of a hybrid-type artificial pancreas. The article discusses construction designs, applied polymeric materials as well as biocompatibility problems of polymeric membranes that encapsulate the Langerhans islets. On example of hydrogel membranes prepared by radiation crosslinking of poly(vinyl alcohol) (PVA) the dependence of the diffusion coefficients of glucose, insulin and immunoglobulin G on the crosslinking degree of hydrogels has been shown.
作者对关于混合型人工胰腺研制的相关工作进行了综述。本文讨论了其结构设计、所应用的聚合材料以及包裹胰岛的聚合物膜的生物相容性问题。以通过聚乙烯醇（PVA）辐射交联制备的水凝胶膜为例，展示了葡萄糖、胰岛素和免疫球蛋白G的扩散系数对水凝胶交联度的依赖性。
