Goode M A, Grauer K, Gums J G
Department of Hospital Pharmacy Practice and Administration, Medical University of South Carolina, Charleston.
Postgrad Med. 1994 Nov 1;96(6):85-8, 91-8.
Vaginal candidiasis, trichomoniasis, and bacterial vaginosis can be difficult to manage because of predisposing factors and frequent recurrence. Thus, in addition to drug therapy, management should include attempts to minimize factors that contribute to recurrence. Both topical and oral agents are available for vaginal candidiasis and bacterial vaginosis, and both routes of administration appear equally safe and effective. Topical therapy may be used for these conditions in pregnant women. Only oral therapy is optimal for trichomoniasis. However, during pregnancy, the infection may be managed with topical clotrimazole. Currently, treatment of a woman's sexual partner is recommended in the management of trichomoniasis and is optional in cases of bacterial vaginosis. Sexual activity may also contribute to the recurrence of vaginal candidiasis; however, more studies are needed to evaluate the impact on recurrence rates of treating the male partner.
由于存在易感因素且复发频繁，阴道念珠菌病、滴虫病和细菌性阴道病可能难以治疗。因此，除药物治疗外，治疗还应包括尽量减少导致复发的因素。局部用药和口服药物均可用于治疗阴道念珠菌病和细菌性阴道病，两种给药途径似乎同样安全有效。局部治疗可用于孕妇的这些疾病。滴虫病仅口服治疗最佳。然而，在孕期，感染可用克霉唑局部治疗。目前，滴虫病治疗建议治疗女性性伴侣，细菌性阴道病病例中可选择治疗性伴侣。性行为也可能导致阴道念珠菌病复发；然而，需要更多研究来评估治疗男性伴侣对复发率的影响。
