Peña C E
Acta Neurol Latinoam. 1975;21(1-4):23-30.
The ultrastructure of a primary reticulum-cell sarcoma (microglioma) of the brain was studied. The main or predominant tumor cells had a relatively abundant perikaryon with peripheral pseudopods and a moderate number of organelles. The nucleus was multilobulated and contained a prominent nucleolus. A second type, or phagocytic cell, had a similar structure but exhibited some distinctive features. The cytoplasm contained numerous lysosomes, phagolysosomes, occasional phagocytized whole cells and abundant organelles, especially Golgi complex. The nucleus was ovoid and nucleoli were smaller. This cell was considered to be a neoplastic element with a higher degree of differentiation. A third group of cells included lymphocytes with various degrees of maturation and/or differentiation as well as plasma cells exhibiting active protein synthesis. It is concluded that the ultrastructural features of the neoplasm are indicative of a reticulohistiocytic nature.
对脑原发性网状细胞肉瘤（微胶质瘤）的超微结构进行了研究。主要或占优势的肿瘤细胞有一个相对丰富的核周体，周围有伪足，细胞器数量适中。细胞核呈多叶状，有一个明显的核仁。第二种类型，即吞噬细胞，具有类似的结构，但表现出一些独特的特征。细胞质中含有大量溶酶体、吞噬溶酶体、偶尔吞噬的完整细胞和丰富的细胞器，尤其是高尔基体。细胞核呈卵圆形，核仁较小。这种细胞被认为是分化程度较高的肿瘤成分。第三组细胞包括不同成熟度和/或分化程度的淋巴细胞以及表现出活跃蛋白质合成的浆细胞。结论是，该肿瘤的超微结构特征表明其具有网状组织细胞性质。
