Eaton S B, Pike M C, Short R V, Lee N C, Trussell J, Hatcher R A, Wood J W, Worthman C M, Jones N G, Konner M J
Department of Radiology, Emory University School of Medicine, Atlanta, Georgia 30322.
Q Rev Biol. 1994 Sep;69(3):353-67. doi: 10.1086/418650.
Reproductive experiences for women in today's affluent Western nations differ from those of women in hunting and gathering societies, who continue the ancestral human pattern. These differences parallel commonly accepted reproductive risk factors for cancers of the breast, endometrium and ovary. Nutritional practices, exercise requirements, and body composition are nonreproductive influences that have been proposed as additional factors affecting the incidence of women's cancers. In each case, these would further increase risk for women in industrialized countries relative to forager women. Lifestyles and reproductive patterns new from an evolutionary perspective may promote women's cancers. Calculations based on a theoretical model suggest that, to age 60, modern Western women have a breast cancer risk as much as 100 times that of preagricultural women.
在当今富裕的西方国家，女性的生殖经历与狩猎采集社会中的女性不同，后者延续着人类的祖先模式。这些差异与乳腺癌、子宫内膜癌和卵巢癌常见的公认生殖风险因素相似。营养习惯、运动需求和身体组成是非生殖方面的影响因素，有人提出这些因素是影响女性癌症发病率的额外因素。在每种情况下，相对于觅食女性而言，这些因素都会进一步增加工业化国家女性患癌的风险。从进化角度来看，全新的生活方式和生殖模式可能会引发女性癌症。基于理论模型的计算表明，到60岁时，现代西方女性患乳腺癌的风险是农业社会前女性的100倍之多。
