Kris-Etherton P M, Derr J A, Mustad V A, Seligson F H, Pearson T A
Department of Nutrition, Pennsylvania State University, University Park 16802.
Am J Clin Nutr. 1994 Dec;60(6 Suppl):1037S-1042S. doi: 10.1093/ajcn/60.6.1037S.
This study compares the plasma cholesterol response with the isoenergetic substitution of a milk chocolate bar (46 g) given daily for a high-carbohydrate snack in healthy young men on a Step 1 Diet. Normocholesterolemic men (n = 42) were fed a Step 1 Diet for 21 d (run-in diet) followed by a 27-d experimental period during which they consumed the same diet plus either a milk chocolate bar or a high-carbohydrate snack; after this they consumed the run-in diet for 21 d followed by the other snack for 27 d. When subjects consumed a milk chocolate bar instead of the high-carbohydrate snack, high-density-lipoprotein (HDL) cholesterol was 0.08 +/- 0.03 mmol/L higher (P < 0.01) and plasma triglycerides were 0.06 +/- 0.03 mmol/L lower (P < 0.05). Substitution of a milk chocolate bar for a high-carbohydrate snack did not adversely affect the low-density-lipoprotein-(LDL) cholesterol response to a Step 1 Diet despite an increase in total fat and saturated fatty acid content of the diet. This response may be due to stearic acid.
本研究比较了在第1阶段饮食的健康年轻男性中,用每日提供的一块牛奶巧克力棒(46克)等量替代高碳水化合物零食后血浆胆固醇的反应。血脂正常的男性(n = 42)先接受21天的第1阶段饮食(磨合期饮食),随后进入为期27天的实验期,在此期间他们食用相同的饮食并搭配一块牛奶巧克力棒或一种高碳水化合物零食;在此之后,他们再食用21天的磨合期饮食,接着食用另一种零食27天。当受试者食用牛奶巧克力棒而非高碳水化合物零食时,高密度脂蛋白(HDL)胆固醇升高了0.08±0.03毫摩尔/升(P < 0.01),血浆甘油三酯降低了0.06±0.03毫摩尔/升(P < 0.05)。用牛奶巧克力棒替代高碳水化合物零食,尽管饮食中的总脂肪和饱和脂肪酸含量有所增加,但并未对低密度脂蛋白(LDL)胆固醇对第1阶段饮食的反应产生不利影响。这种反应可能归因于硬脂酸。