类风湿关节炎患者滑液中未检测到结核分枝杆菌DNA。
Absence of Mycobacterium tuberculosis DNA in synovial fluid from patients with rheumatoid arthritis.
作者信息
Jalal H, Millar M, Linton C, Dieppe P
机构信息
Department of Pathology and Microbiology, University of Bristol, United Kingdom.
出版信息
Ann Rheum Dis. 1994 Oct;53(10):695-8. doi: 10.1136/ard.53.10.695.
Abstract
OBJECTIVES
To determine whether Mycobacterium tuberculosis DNA can be detected in synovial fluid of patients with rheumatoid arthritis (RA).
METHODS
The polymerase chain reaction was applied to cellular components of synovial fluid.
RESULTS
No evidence of M tuberculosis DNA was found in synovial fluid from 31 patients with RA and 13 control patients.
CONCLUSION
The findings do not support a role for persistent M tuberculosis infection in the pathogenesis of RA.
摘要
目的
确定类风湿关节炎（RA）患者的滑液中是否能检测到结核分枝杆菌DNA。
方法
将聚合酶链反应应用于滑液的细胞成分。
结果
在31例RA患者和13例对照患者的滑液中未发现结核分枝杆菌DNA的证据。
结论
这些发现不支持持续性结核分枝杆菌感染在RA发病机制中的作用。
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