McGuire H H
Surgical Service, McGuire Veterans Affairs Medical Center, Richmond, Virginia.
Ann Surg. 1994 Nov;220(5):653-6. doi: 10.1097/00000658-199411000-00008.
The study was undertaken to correct or reaffirm current recommendations based on old observations of doubtful validity because of their lack of routine colonoscopy, scintigraphy, or angiography.
Patterns of bleeding were derived from transfusion records of 78 patients admitted 106 times for lower gastrointestinal bleeding with no detectable cause other than colon diverticula.
Bleeding stopped spontaneously in 82 of 108 episodes and in 66 of 67 patients requiring less than four units of transfusion on any day. When four or more units were required in a day, 25 of 42 patients required emergency surgery. When a bleeding site was identified and removed, only 1 of 25 patients bled again from another diverticulum. After discharge without surgery, 28 of 73 began to bled again. After "blind" colectomy and ileoproctostomy, four of seven patients developed leaks or abscesses, and two died.
Bleeding stopped spontaneously in 75% of episodes and in 99% of patients requiring less than four units of transfusion per day. Bleeding continued in 25% of episodes and in most patients who required four or more units per day. Bleeding sites of those patients who continued to bleed were shown by scintigraphy or angiography. When a bleeding diverticulum is removed, rebleeding is rare. "Blind" resection is unsafe.
由于缺乏常规结肠镜检查、闪烁扫描或血管造影,以往一些有效性存疑的观察结果被用于制定当前建议,本研究旨在纠正或重新确认这些建议。
从78例因下消化道出血入院106次的患者输血记录中得出出血模式,这些患者除结肠憩室外无其他可检测到的病因。
108次出血发作中有82次出血自行停止,67例每天输血少于4单位的患者中有66例出血自行停止。当一天需要4单位或更多单位输血时,42例患者中有25例需要急诊手术。当确定并切除出血部位后,25例患者中只有1例从另一个憩室再次出血。未经手术出院后,73例患者中有28例再次出血。在“盲目”结肠切除术和回肠直肠吻合术后,7例患者中有4例出现渗漏或脓肿,2例死亡。
75%的出血发作和99%每天输血少于4单位的患者出血自行停止。25%的出血发作和大多数每天需要4单位或更多单位输血的患者出血持续。继续出血患者的出血部位通过闪烁扫描或血管造影显示。切除出血憩室后,再次出血很少见。“盲目”切除不安全。