Malthaner R A, Tood T R, Miller L, Pearson F G
Division of Thoracic Surgery, Toronto Hospital, University of Toronto, Ontario, Canada.
Ann Thorac Surg. 1994 Nov;58(5):1343-6; discussion 1346-7. doi: 10.1016/0003-4975(94)91910-0.
The long-term clinical results of surgical treatment for esophageal achalasia were reviewed in 35 patients having a minimum follow-up of 10 years. Group A (n = 22) are those patients whose first procedure (myotomy and Belsey partial fundoplication) was done at our hospital. Group B (n = 13) are those who had undergone one or more previous operations elsewhere. In group A good to excellent results occurred in 21/22 patients (95%) at 1 year, 17/22 (77%) at 5 years, 15/22 (68%) at 10 years, 11/16 (69%) at 15 years, and 6/9 (67%) at 20 or more years. Two patients underwent early reoperation (2 and 5 years) for dysphagia due to incomplete myotomy. Three patients underwent esophagectomy (7, 19, and 23 years) and one patient underwent an antrectomy and Roux-en-Y diversion (23 years) for late-onset complications of reflux. Three of 13 group B patients had had multiple prior operations and had severe reflux damage at presentation and underwent immediate esophagectomy. Ten patients had one or more conservative operations in our hospital, and 4 of these eventually required esophagectomy for disabling reflux. Therefore, there were 10 patients (groups A+B) who underwent esophageal resection, all but 1 of whom had endoscopically documented reflux and 5 of whom had peptic strictures. Six of the 10 esophagectomies were performed more than 10 years (13 to 23 years) after the first operation.(ABSTRACT TRUNCATED AT 250 WORDS)
对35例接受手术治疗的贲门失弛缓症患者进行了长期临床结果回顾,这些患者的最短随访时间为10年。A组(n = 22)是那些首次手术(肌切开术和Belsey部分胃底折叠术)在我院进行的患者。B组(n = 13)是那些先前在其他地方接受过一次或多次手术的患者。A组中,21/22例患者(95%)在1年时效果良好至极佳,17/22例(77%)在5年时,15/22例(68%)在10年时,11/16例(69%)在15年时,6/9例(67%)在20年或更长时间时。2例患者因肌切开术不完全导致吞咽困难而早期再次手术(分别在2年和5年)。3例患者因反流的晚期并发症接受了食管切除术(分别在7年、19年和23年),1例患者接受了胃窦切除术和Roux-en-Y转流术(23年)。B组13例患者中有3例曾接受多次先前手术,就诊时存在严重反流损伤,立即接受了食管切除术。10例患者在我院接受了一次或多次保守手术,其中4例最终因致残性反流需要进行食管切除术。因此,有10例患者(A组+B组)接受了食管切除术,除1例患者外,所有患者内镜检查均证实有反流,其中5例有消化性狭窄。10例食管切除术中,有6例是在首次手术后10年以上(13至23年)进行的。(摘要截断于250字)