Onghena P, Edgington E S
Katholieke Universiteit Leuven, Department of Psychology, Belgium.
Behav Res Ther. 1994 Sep;32(7):783-6. doi: 10.1016/0005-7967(94)90036-1.
Alternating Treatments Designs (ATD) with random assignment of the treatments to the measurement times provide very powerful single-case experiments. However, complete randomization might cause too many consecutive administrations of the same treatment to occur in the design. In order to exclude these possibilities, an ATD with restricted randomization can be used. In this article we provide a general rationale for the random assignment procedure in such a Restricted Alternating Treatments Design (RATD), and derive the corresponding randomization test. A software package for randomization tests in RATD, ATD and other single-case experimental designs [Van Damme & Onghena Single-case randomization tests, version 1.1, Department of Psychology, Katholieke Universiteit Leuven, Belgium] is discussed.
将治疗随机分配到测量时间点的交替治疗设计（ATD）提供了非常强大的单病例实验。然而，完全随机化可能会导致在设计中出现太多连续的相同治疗给药情况。为了排除这些可能性，可以使用具有受限随机化的交替治疗设计。在本文中，我们为这种受限交替治疗设计（RATD）中的随机分配程序提供了一般原理，并推导了相应的随机化检验。还讨论了一个用于RATD、ATD和其他单病例实验设计的随机化检验的软件包[范·达姆 & 翁赫纳 单病例随机化检验，版本1.1，比利时鲁汶天主教大学心理学系]。
