Mertens D J, Kavanagh T, Shephard R J
Toronto Rehabilitation Centre, Canada.
Eur Heart J. 1994 Sep;15(9):1247-51. doi: 10.1093/oxfordjournals.eurheartj.a060660.
Exercise prescription has traditionally been based on the heart rate/work rate relationship. Many post-myocardial (MI) patients are now taking medications such as beta-blockers that alter this relationship, necessitating an alternative method for exercise prescription. The directly measured maximal oxygen intake (VO2max) is not substantially affected by such medications, but direct determinations of VO2max are time consuming, costly, and vulnerable to both local muscle weakness and poor motivation. We have therefore re-examined the relationship between work rate and maximal oxygen intake in order to derive a simple formula which will give an indirect estimate of the latter. Our results, obtained on 28 patients receiving beta-blockers, 13 receiving calcium channel blockers, 10 receiving combined therapy, and 49 who received neither treatment, indicate that the peak oxygen intake can be estimated accurately, using the expression VO2max.ml.min-1 = 2W, where W is the peak power output, measured in kp.m.min-1, or 12.3 W, where W is the peak power output in Watts.
传统上，运动处方是基于心率与工作率的关系制定的。现在，许多心肌梗死（MI）后患者正在服用如β受体阻滞剂等药物，这些药物会改变这种关系，因此需要一种替代的运动处方方法。直接测量的最大摄氧量（VO2max）受此类药物的影响不大，但直接测定VO2max既耗时、成本高，又容易受到局部肌肉无力和动力不足的影响。因此，我们重新审视了工作率与最大摄氧量之间的关系，以便得出一个能间接估计后者的简单公式。我们对28名服用β受体阻滞剂的患者、13名服用钙通道阻滞剂的患者、10名接受联合治疗的患者以及49名未接受任何治疗的患者进行了研究，结果表明，使用表达式VO2max.ml.min-1 = 2W（其中W是以kp.m.min-1为单位测量的峰值功率输出）或12.3W（其中W是以瓦特为单位的峰值功率输出），可以准确估计峰值摄氧量。
