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Increased incidence of diabetes mellitus in specific pathogen-eliminated offspring produced by embryo transfer in NOD mice with low incidence of the disease.

作者信息

Ohsugi T, Kurosawa T

机构信息

Institute of Experimental Animal Sciences, Osaka University Medical School, Suita, Japan.

出版信息

Lab Anim Sci. 1994 Aug;44(4):386-8.

PMID:7983856
Abstract
摘要

相似文献

1
Increased incidence of diabetes mellitus in specific pathogen-eliminated offspring produced by embryo transfer in NOD mice with low incidence of the disease.在疾病发病率较低的非肥胖糖尿病（NOD）小鼠中，通过胚胎移植产生的特定病原体清除后代中糖尿病发病率增加。
Lab Anim Sci. 1994 Aug;44(4):386-8.
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Short administration of polyclonal anti-T cell antibody (ALS) in NOD mice with extensive insulitis prevents subsequent development of autoimmune diabetes.在患有广泛胰岛炎的非肥胖糖尿病（NOD）小鼠中短期给予多克隆抗T细胞抗体（抗淋巴细胞血清，ALS）可预防自身免疫性糖尿病的后续发展。
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A multi-centre, blinded international trial of the effect of A(1) and A(2) beta-casein variants on diabetes incidence in two rodent models of spontaneous Type I diabetes.一项关于A(1)和A(2)β-酪蛋白变体对两种自发性I型糖尿病啮齿动物模型糖尿病发病率影响的多中心、双盲国际试验。
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Extracellular matrix distribution and islet morphology in the early postnatal pancreas: anomalies in the non-obese diabetic mouse.出生后早期胰腺的细胞外基质分布与胰岛形态：非肥胖型糖尿病小鼠的异常情况
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NOD fetal thymus organ culture: an in vitro model for the development of T cells involved in IDDM.非肥胖型糖尿病（NOD）胎儿胸腺器官培养：一种用于研究参与胰岛素依赖型糖尿病（IDDM）的T细胞发育的体外模型。
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Young NOD mice show increased diabetes sensitivity to low doses of streptozotocin.年轻的非肥胖糖尿病（NOD）小鼠对低剂量链脲佐菌素表现出更高的糖尿病易感性。
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Retrospective observation of the effect of accidental exposure to organophosphates on the success of embryo transfer in mice.意外接触有机磷酸酯对小鼠胚胎移植成功率影响的回顾性观察
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The microbial product lipopolysaccharide confers diabetogenic potential on the T cell repertoire of BDC2.5/NOD mice: implications for the etiology of autoimmune diabetes.微生物产物脂多糖赋予BDC2.5/NOD小鼠的T细胞库致糖尿病潜能：对自身免疫性糖尿病病因的启示。
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Interactions between the microbiota and the immune system.微生物群与免疫系统的相互作用。
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Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes status.电化学发光法检测的胰岛素抗体可预测非肥胖型糖尿病小鼠胰岛炎的严重程度和发病，并可区分人类 1 型糖尿病的状态。
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Expert Rev Clin Immunol. 2010 Nov;6(6):939-55. doi: 10.1586/eci.10.68.
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Modulation of diabetes in NOD mice by GAD65-specific monoclonal antibodies is epitope specific and accompanied by anti-idiotypic antibodies.GAD65特异性单克隆抗体对NOD小鼠糖尿病的调节具有表位特异性，并伴有抗独特型抗体。
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