Sakharova I I
Probl Tuberk. 1994(4):51-3.
The paper gives cytochemical findings of the lysosomal cationic system of neutrophilic granulocytes in the blood of 188 patients with various pulmonary tuberculoses. In infiltrative pulmonary tuberculosis which was first detected, the decrease in the activity of the lysosomal cationic system of neutrophils was adequate to the extent and severity of the process. The permanent increase in the antimicrobial potential of neutrophilic granulocytes in patients with fibrous and cavernous pulmonary tuberculosis is a defense response of the body, however with constantly progressive tuberculosis, there is inhibition of this defense system, which becomes an unfavourable sign. It can be assumed that the parameters of the activity of bactericidal systems in the neutrophilic granulocytes reflect, to a greater extent, both the activity of this system and the resistance of the whole body.
本文给出了188例不同类型肺结核患者血液中嗜中性粒细胞溶酶体阳离子系统的细胞化学研究结果。在初发的浸润性肺结核中，嗜中性粒细胞溶酶体阳离子系统活性的降低与病变的范围和严重程度相适应。纤维空洞型肺结核患者嗜中性粒细胞抗菌潜能的持续增加是机体的一种防御反应，然而，在病情不断进展的肺结核中，这种防御系统会受到抑制，这成为一个不良迹象。可以认为，嗜中性粒细胞中杀菌系统的活性参数在很大程度上既反映了该系统的活性，也反映了全身的抵抗力。
