Claesson B A, Leinonen M
Department of Infectious Diseases, University of Göteborg, Sweden.
Scand J Infect Dis. 1994;26(4):399-402. doi: 10.3109/00365549409008611.
In 284 Swedish children with community-acquired, roentgenologically verified pneumonia, antibodies to Moraxella (Branhamella) catarrhalis were determined in paired serum samples with an enzyme immunoassay using a whole-cell antigen preparation from 10 strains of M. catarrhalis. Only 9 children (3%) had significant increases in antibodies to M. catarrhalis. Among these 9 children, 11-39 months of age, 6 had serologic evidence of concurrent infection with other respiratory pathogens such as S. pneumoniae, non-capsulated H. influenza, RS virus and adenovirus. In 6 (67%) of the 9 children with antibody response and in 74 (27%) of the 275 children without antibody response to M. catarrhalis, nasopharyngeal cultures yielded growth of this bacterium. M. catarrhalis seems to be a common commensal in the upper respiratory tract, but a rare cause of pneumonia in children.
在284名患有社区获得性、经X线检查证实为肺炎的瑞典儿童中，采用酶免疫测定法，以10株卡他莫拉菌的全细胞抗原制剂，对配对血清样本中的卡他莫拉菌（布兰汉菌属）抗体进行了测定。只有9名儿童（3%）的卡他莫拉菌抗体有显著升高。在这9名年龄在11至39个月的儿童中，有6名有血清学证据表明同时感染了其他呼吸道病原体，如肺炎链球菌、无荚膜流感嗜血杆菌、呼吸道合胞病毒和腺病毒。在9名对卡他莫拉菌有抗体反应的儿童中有6名（67%），在275名对卡他莫拉菌无抗体反应的儿童中有74名（27%），鼻咽部培养物培养出了这种细菌。卡他莫拉菌似乎是上呼吸道常见的共生菌，但却是儿童肺炎的罕见病因。
