Korppi M, Katila M L, Jääskeläinen J, Leinonen M
Department of Paediatrics and Clinical Microbiology, Kuopio University Hospital, Finland.
Acta Paediatr. 1992 Dec;81(12):993-6. doi: 10.1111/j.1651-2227.1992.tb12161.x.
During a 12-month surveillance period in 1981-1982, Moraxella catarrhalis was detected in cultures from nasopharyngeal aspirates from 76 (17%) of 449 children hospitalized with middle or lower respiratory tract infection. Seroconversion to M. catarrhalis was positive in 4 (5%) of the 76 patients with M. catarrhalis present in nasopharyngeal aspirates and in 4 (1%) of 373 patients with a negative finding. Although children with respiratory tract infections were often colonized by the organism, this was rarely the infective agent of the middle or lower airways. Four of 8 patients with seroconversion to M. catarrhalis exhibited a concomitant RSV infection. The carriage of this species was more closely associated with parainfluenza virus infections. Serological responses to M. catarrhalis were not associated with acute otitis media, and were also rare in children with pneumonia. It is concluded that bronchopulmonary infections caused by M. catarrhalis are rare in children, and that M. catarrhalis aetiology need not be considered in the selection of antibiotics in cases of community-acquired pneumonia or other infections of the middle or lower respiratory tract affecting primarily healthy children.
在1981 - 1982年为期12个月的监测期内，从449名因上、下呼吸道感染住院的儿童的鼻咽抽吸物培养物中检测到卡他莫拉菌的有76名（17%）。在鼻咽抽吸物中检测到卡他莫拉菌的76名患者中，有4名（5%）血清转化为阳性，在373名检测结果为阴性的患者中有4名（1%）血清转化为阳性。虽然呼吸道感染儿童常被该菌定植，但它很少是上、下呼吸道的感染病原体。8名血清转化为卡他莫拉菌的患者中有4名同时感染了呼吸道合胞病毒（RSV）。该菌的携带与副流感病毒感染关系更为密切。对卡他莫拉菌的血清学反应与急性中耳炎无关，在肺炎患儿中也很少见。结论是，卡他莫拉菌引起的支气管肺部感染在儿童中很少见，在社区获得性肺炎或其他主要影响健康儿童的上、下呼吸道感染病例中，选择抗生素时无需考虑卡他莫拉菌病因。
