Schulte A, Stoll R, Wittich M, Pieper K, Stachniss V
Medizinisches Zentrum für Zahn-, Mund- und Kieferheilkunde, Universität Marburg.
Schweiz Monatsschr Zahnmed. 1994;104(11):1336-40.
Studies on adults documented that most of the urinary concentration in occupationally non-exposed persons is determined by the number and extent of their amalgam fillings. Very few data concerning the mercury exposure of children are available. In this study the mercury concentration in the urine of 3-15-year-old children with and without amalgam fillings was determined. The mean urinary mercury concentration for the children without amalgam (n = 93) was 0.17 microgram/l, and for the children with amalgam fillings (n = 86) it was 0.70 microgram/l. The creatinine adjusted values were 0.19 microgram/g and 0.64 microgram/g, respectively. This difference was significant (p < 0.001). Also, a significant correlation was found between the number of amalgam points (each amalgam surface had been given 1 to 3 points depending on its extent) and the urinary mercury concentration (r = 0.69).
针对成年人的研究表明，职业上未接触汞的人群中，大部分尿液汞浓度由其汞合金补牙的数量和范围决定。关于儿童汞暴露的可用数据极少。在本研究中，测定了有和没有汞合金补牙的3至15岁儿童尿液中的汞浓度。没有汞合金补牙的儿童（n = 93）尿液汞浓度平均值为0.17微克/升，有汞合金补牙的儿童（n = 86）尿液汞浓度平均值为0.70微克/升。肌酐校正值分别为0.19微克/克和0.64微克/克。这种差异具有显著性（p < 0.001）。此外，还发现汞合金补牙点数（根据汞合金表面范围，每个表面给予1至3个点）与尿液汞浓度之间存在显著相关性（r = 0.69）。
