Muschter R, Perlmutter A P
Urologische Klinik Grosshadern, Munich, Germany.
Urology. 1994 Dec;44(6):856-61. doi: 10.1016/s0090-4295(94)80170-3.
To evaluate the laser-tissue interaction during neodymium:yttrium-aluminum-garnet (Nd:YAG) irradiation using right angle firing fibers in motion, contact vaporization applicators, and interstitial lightguides.
The heating patterns and coagulation volumes created during right angle firing fiber pulling and painting, contact tip vaporization, and interstitial thermotherapy were studied in potato and canine models.
High power density right angle firing fibers can be used in motion to create coagulation lesions at 40 and 60 watts (W). The depth of such lesions was less than that obtained during fixed free beam side fire coagulation. Contact vaporization applicators caused tissue vaporization without creating concurrent coagulation lesions. Interstitial lightguide thermotherapy created coagulation lesions without carbonization using A step power reduction approach during irradiation.
Each of the investigated methods had the ability to destroy prostate tissue, and therefore may have a role in the evolution of laser prostatectomy.
评估使用直角发射光纤在移动、接触汽化施器和间质光导的情况下进行钕：钇铝石榴石（Nd：YAG）激光照射期间的激光-组织相互作用。
在土豆和犬模型中研究了直角发射光纤牵拉和涂抹、接触尖端汽化以及间质热疗过程中产生的加热模式和凝固体积。
高功率密度直角发射光纤可在移动中使用，在40瓦（W）和60瓦时产生凝固性病变。此类病变的深度小于固定自由光束侧射凝固时获得的深度。接触汽化施器导致组织汽化，而不会同时产生凝固性病变。间质光导热疗在照射期间采用逐步降低功率的方法产生无碳化的凝固性病变。
每种研究方法都有能力破坏前列腺组织，因此可能在激光前列腺切除术的发展中发挥作用。
