7例有机汞中毒（水俣病）患者的磁共振成像（MR）表现。
MR findings in seven patients with organic mercury poisoning (Minamata disease).
作者信息
Korogi Y, Takahashi M, Shinzato J, Okajima T
机构信息
Department of Radiology, Kumamoto University School of Medicine, Japan.
出版信息
AJNR Am J Neuroradiol. 1994 Sep;15(8):1575-8.
PURPOSE
To study the long-term MR findings in seven patients with Minamata disease.
METHODS
All patients examined were affected after eating daily considerable amounts of the methylmercury-contaminated seafoods from 1955 through 1958 and showed typical neurologic findings. T1- and T2-weighted images were obtained in axial, coronal, and sagittal sections.
RESULTS
The visual cortex, the cerebellar vermis and hemispheres, and the postcentral cortex were significantly atrophic. The visual cortex was slightly hypointense on T1-weighted images and hyperintense on T2-weighted images, probably representing the pathologic changes of status spongiosus.
CONCLUSION
MR demonstrated the lesions, located in the calcarine area, cerebellum, and postcentral gyri, which are probably related to three of the characteristic manifestations of this disease: the constriction of the visual fields, ataxia, and sensory disturbance, respectively.
目的
研究七名水俣病患者的长期磁共振成像（MR）表现。
方法
所有接受检查的患者在1955年至1958年期间每日食用大量受甲基汞污染的海产品后患病，并表现出典型的神经学症状。在轴位、冠状位和矢状位获取T1加权像和T2加权像。
结果
视皮质、小脑蚓部和半球以及中央后皮质显著萎缩。视皮质在T1加权像上略呈低信号，在T2加权像上呈高信号，可能代表海绵状状态的病理改变。
结论
MR显示病变位于距状区、小脑和中央后回，可能分别与该疾病的三种特征性表现有关：视野缩小、共济失调和感觉障碍。
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