Poscher M E
Department of Medicine, University of California/Mount Zion Medical Center, San Francisco.
AIDS. 1994 Aug;8(8):1115-7.
Neurologic complications are common in patients with AIDS. Herpes zoster is a common early manifestation of HIV infection, but there have been few reports of encephalitic complications and nearly all have been postmortem. We report four cases of varicella zoster virus (VZV) meningoencephalitis diagnosed and treated antemortem, and briefly review the relevant literature.
Mount Zion Medical Center, San Francisco, California, USA.
Four HIV-positive male patients with antibodies to VZV in their cerebrospinal fluid.
Treatment with intravenous acyclovir (three cases) and intravenous ganciclovir (one case), which resulted in resolution of all symptoms except blindness in one patient.
Antibodies to VZV in the cerebrospinal fluid of HIV-positive individuals may allow early diagnosis and lifesaving treatment of VZV meningoencephalitis.
神经系统并发症在艾滋病患者中很常见。带状疱疹是HIV感染的常见早期表现，但关于脑炎并发症的报道很少，几乎所有报道都是尸检后的。我们报告4例生前诊断和治疗的水痘-带状疱疹病毒（VZV）脑膜脑炎病例，并简要回顾相关文献。
美国加利福尼亚州旧金山锡安山医疗中心。
4名脑脊液中存在VZV抗体的HIV阳性男性患者。
3例患者接受静脉注射阿昔洛韦治疗，1例患者接受静脉注射更昔洛韦治疗，除1例患者失明外，所有症状均得到缓解。
HIV阳性个体脑脊液中VZV抗体可实现VZV脑膜脑炎的早期诊断和挽救生命的治疗。
