Fouad-Tarazi F M
Cleveland Clinic Foundation, Department of Cardiology, OH 44195.
Curr Opin Cardiol. 1994 Sep;9(5):551-60. doi: 10.1097/00001573-199409000-00008.
Abnormalities of left ventricular diastolic function in hypertension are multifactorial in origin. Of importance is the demonstration that abnormalities of left ventricular filling in hypertension may be accompanied by deleterious cardiovascular neurodynamic regulations. However, the left ventricular filling rates can be normalized during medical treatment of hypertension. In particular, regression of left ventricular hypertrophy is almost always associated with or followed by improvement of left ventricular filling. The effects of this normalization on cardiovascular dynamics and the outcome of hypertensive heart disease are yet to be demonstrated.
高血压患者左心室舒张功能异常的起源是多因素的。重要的是，有证据表明高血压患者左心室充盈异常可能伴有有害的心血管神经动力学调节。然而，在高血压的药物治疗过程中，左心室充盈率可以恢复正常。特别是，左心室肥厚的消退几乎总是与左心室充盈改善相关或随后出现左心室充盈改善。这种正常化对心血管动力学和高血压性心脏病预后的影响尚待证实。
