必需脂肪酸缺乏对大鼠上颌骨和下颌骨脂肪酸组成及花生四烯酸水平的影响。
Effect of essential fatty acid deficiency on the fatty acid composition and arachidonic acid levels in rat maxillae and mandibles.
作者信息
Alam S Q, Henderson M, Alam B S
机构信息
Department of Biochemistry and Molecular Biology, LSU Medical Center, New Orleans 70119.
出版信息
Calcif Tissue Int. 1994 Sep;55(3):169-72. doi: 10.1007/BF00425870.
The fatty acid composition of total lipids and total phospholipids of maxillae and mandibles of rats fed an essential fatty acid-deficient (EFAD), marginally FAD (MEFAD), and a control diet was determined. Patterns typical of an EFA deficiency such as a decrease in the levels of linoleic acid and archidonic acid along with concomitant increase in the levels of palmitoleic acid, oleic acid, and 5,8,11-eicosatrienoic acid were observed in the EFAD groups. Concentrations of arachidonic acid were significantly lower in total lipids of mandibles and maxillae of rats in the EFAD, but not in the MEFAD rats, than those of the controls.
测定了喂食必需脂肪酸缺乏（EFAD）、边缘性必需脂肪酸缺乏（MEFAD）和对照饮食的大鼠上颌骨和下颌骨中总脂质和总磷脂的脂肪酸组成。在EFAD组中观察到了典型的必需脂肪酸缺乏模式，如亚油酸和花生四烯酸水平降低，同时棕榈油酸、油酸和5,8,11-二十碳三烯酸水平升高。与对照组相比，EFAD组大鼠下颌骨和上颌骨总脂质中花生四烯酸的浓度显著降低，但MEFAD组大鼠未出现这种情况。
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