Gyorkos T W, Tannenbaum T N, Abrahamowicz M, Bédard L, Carsley J, Franco E D, Delage G, Miller M A, Lamping D L, Grover S A
Division of Clinical Epidemiology, Montreal General Hospital, Montreal, Quebec.
Can J Public Health. 1994 Jul-Aug;85 Suppl 1:S14-30.
Scientific evidence documenting the effectiveness of immunization delivery methods was summarized using the generic approach developed by the Community Health Practice Guidelines Working Group. The delivery methods examined were those for the adult and childhood vaccines of influenza, pneumococcal infection, hepatitis B, measles-mumps-rubella and diphtheria-pertussis-tetanus-polio. Based on a critical appraisal of 54 eligible comparative studies, the effects of different interventions were obtained and pooled effects were calculated for delivery methods oriented to the client, the provider and the system. The results indicate those interventions found to be most effective for each vaccine. This review of the scientific evidence of the effectiveness of immunization delivery methods provides a base for policy development and assists in the planning of resource allocation.
利用社区卫生实践指南工作组制定的通用方法，总结了记录免疫接种实施方法有效性的科学证据。所研究的实施方法包括成人和儿童流感疫苗、肺炎球菌感染疫苗、乙型肝炎疫苗、麻疹-腮腺炎-风疹疫苗以及白喉-百日咳-破伤风-脊髓灰质炎疫苗的接种方法。基于对54项符合条件的对照研究的严格评估，得出了不同干预措施的效果，并计算了针对服务对象、服务提供者和系统的实施方法的合并效果。结果表明了对每种疫苗最有效的干预措施。对免疫接种实施方法有效性的科学证据进行的这项综述为政策制定提供了依据，并有助于资源分配规划。
