Potente F, Ghiron U, Caramia M, Seglie E, Fava F, Rolfo F
Divisione di Chirurgia Generale, Ospedale S. Croce di Moncalieri, Torino.
Minerva Chir. 1994 Sep;49(9):787-90.
Carcinoma of the gallbladder is the most frequent neoplasm of the biliary tract. During the period between 1 January 1979 and 31 December 1991 a total of 1016 operations for cholecystectomy were performed by our Division of Surgery and 27 cases of gallbladder carcinoma were diagnosed. The symptoms were generally similar to those of benign hepatobiliary disorders. The diagnostic tests carried out did not allow a preoperative diagnosis of gallbladder carcinoma to be made. In the majority of cases diagnosis was a surprise following the histological analysis of the operated part. The prime therapy for these lesions is surgery. Since it is not possible to make an early diagnosis of this type of neoplasm, which in the majority of cases has a fatal prognosis, the authors consider that the finding of inveterate calculosis, large calculi and echographic thickening of the gallbladder wall represent indications for surgery even in the absence of major symptoms.
胆囊癌是胆道最常见的肿瘤。在1979年1月1日至1991年12月31日期间,我们外科共进行了1016例胆囊切除术,其中诊断出27例胆囊癌。其症状通常与良性肝胆疾病相似。所进行的诊断检查无法在术前诊断出胆囊癌。在大多数情况下,诊断是在对手术部位进行组织学分析后才意外得出的。这些病变的主要治疗方法是手术。由于无法对这类肿瘤进行早期诊断,而这类肿瘤在大多数情况下预后是致命的,因此作者认为,即使没有主要症状,发现顽固性结石病、大结石和胆囊壁超声增厚也表明需要进行手术。