Molina-Carballo A, Muñóz-Hoyos A, Rodríguez-Cabezas T, Acuña-Castroviejo D
Grupo de Investigacion Subnormalidad y Desarrollo Infantil, Hospital Universitario de Granada, Spain.
Psychiatry Res. 1994 Jun;52(3):273-83. doi: 10.1016/0165-1781(94)90073-6.
The pineal gland is a complex neuroendocrine organ with pronounced effects on central nervous system activity. Because previous studies in animals and humans have suggested an anticonvulsant role for the pineal hormone melatonin, we studied the day-night variations in plasma melatonin in normal children and children with febrile or epileptic convulsions. We found significant changes in day-night melatonin levels during convulsions, consistent with the hypothesis that melatonin has an inhibitory function on central nervous system activity.
松果体是一个复杂的神经内分泌器官，对中枢神经系统活动有显著影响。由于之前在动物和人类中的研究表明松果体激素褪黑素具有抗惊厥作用，我们研究了正常儿童以及患有热性惊厥或癫痫性惊厥儿童血浆褪黑素的昼夜变化。我们发现惊厥期间血浆褪黑素水平有显著变化，这与褪黑素对中枢神经系统活动具有抑制作用的假说一致。
