Aleksandrova L Z, Nasonov E L, Chankov S V, Samsonov M Iu, Ovtrakht N V, Titov V N
Ter Arkh. 1994;66(9):69-70.
Quantitation of neopterin and morphological examination of bacteria circulating in the blood of 28 patients with dilated cardiomyopathy gave evidence for elevated neopterin concentrations in 22 of the examinees (> 10 nM/l). The highest neopterin levels occurred in patients with L-form bacteria. Concentrations of neopterin and antibodies to cytomegalovirus, herpes simplex were related. The above antibodies were associated with high neopterin levels in the serum. It is suggested that high amounts of serum neopterin may result from combination of viral and bacterial infection in dilated cardiomyopathy sufferers.
对28例扩张型心肌病患者血液中蝶呤的定量分析以及对循环细菌的形态学检查发现，22名受检者（>10 nM/l）的蝶呤浓度升高。蝶呤水平最高的是L型细菌感染的患者。蝶呤浓度与巨细胞病毒、单纯疱疹病毒抗体相关。上述抗体与血清中高蝶呤水平有关。提示扩张型心肌病患者血清中大量蝶呤可能是病毒和细菌感染共同作用的结果。
