会阴部神经刺激用于控制尿道括约肌。实验研究。

Perineal nerve stimulation for urinary sphincter control. Experimental study.

作者信息

Shafik A

出版信息

Urol Res. 1994;22(3):151-5. doi: 10.1007/BF00571842.

Abstract

The effect of electrostimulation of the perineal nerve on the external urethral sphincter (EUS) and urethral pressure was studied in 9 dogs. The nerve was displayed in the ischiorectal fossa through a para-anal incision and an electrode was applied to it. Perineal nerve stimulation effected an increase of the urethral pressure (P < 0.01) and EMG activity of the EUS (P < 0.01), but not of the vesical pressure (P > 0.05). The greater the stimulus frequency, the higher the rise of the urethral pressure and EUS activity up to 50 Hz beyond which no further increase occurred. The duration of response diminished with increased frequency, the shortest being at 80 Hz (P < 0.001). The latency of the response decreased with increased stimulus frequency (P < 0.05). In terms of force and speed of contraction, stimulus frequency of 50 Hz evokes the most adequate EUS contraction. An off-time of double the stimulation phase allows indefinite re-stimulation. Chronic electrostimulation of the perineal nerve may restore the sphincter tone so that perineal stimulation could be dispensed with.

摘要

在9只犬中研究了会阴神经电刺激对外尿道括约肌（EUS）和尿道压力的影响。通过肛门旁切口在坐骨直肠窝显露神经，并将电极置于其上。会阴神经刺激使尿道压力升高（P<0.01），EUS的肌电图活动增强（P<0.01），但膀胱压力无变化（P>0.05）。刺激频率越高，尿道压力和EUS活动升高越明显，直至50Hz，超过该频率则不再进一步升高。反应持续时间随频率增加而缩短，在80Hz时最短（P<0.001）。反应潜伏期随刺激频率增加而缩短（P<0.05）。就收缩力和速度而言，50Hz的刺激频率可引起最适当的EUS收缩。刺激期两倍的间歇期可允许无限次再刺激。会阴神经的慢性电刺激可恢复括约肌张力，从而可无需会阴刺激。